The Concentration High-Density Lipoprotein in the Menopausal Transition

Abstract

Menopausal transition is a period characterised by psychic, somatic changes as well as changes in reproductive capabilities of a woman as a consequence of ovarian’s function termination. Menopausal transition includes the stage of premenopause and perimenopause, to reach finally the menopause stage itself. The aim of this study is to determine the differences in HDL concentrations at women in premenopause, perimenopause and postmenopause, and to determine the connection between BMI and WHR with HLD concentrations during the menopausal transition, as well as to determine the relation between menarche and length of reproductive age with HDL concentrations in menopausal transition. The assesses included in this study were aged from 40 to 55, with average age 48.1 ± 3.9 years. The biggest average HDL value was found at the group of postmenopausal assessees(1.65 mmol/L), and in comparison with the values in other two groups, there is a significant difference (F=4.23, p=0.016). Based on the obtained results, we cannot conclude that there is a significant relation between menarche and length of reproductive age and HDL among the premenopausal and postmenopausal assessees. There is also a significant difference between WHR and HDL among the premenopausal and perimenopausal assesses. In this study, we obtained astonishing result in comparison with the studies and researches done so far, primarily referring to increased HDL at perimenopausal and postmenopausal assessees.