Trends in Statin Consumption and Cardiovasvular Mortality in Croatia 2004 – 2012
Abstract
Prescribing of statins showed an increasing trend in all developed countries, during the last two
decades. The aim of this study was to research the trends in statins consumption in the period
from 2004 to 2012 as well as the trends of cardiovascular mortality during the 1990 to 2012
period, and to compare it between Croatia and several neighbouring countries. Data on statins
expenditures and consumption expresed in DDD/TID, were taken from annual reports of
Croatian Agency for Medicinal Products and Medical Devices (HALMED). Data on crude
Mortality rates and standardized cardiovascular mortality rates, were taken from the Croatian
Health Statistics Yearbooks. During the observed period utilization of statins increased by
196,7% with the highest consumption of atorvastatin and simvastatin. Financial expenditure of
statins expanded at much faster rate in comparison with drug costs in total. Cardiovascular
mortality rates decreased slightly, while maintaining higher level in comparison with some
neighbouring countries.
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